Matchup
You are stronger late game — farm safe and avoid early trades.
Build vs Yuumi
Build adapted to this matchup
Starting items
Core build
Standard
Summoner spells
100%Anti AD
Anti AP
DPS
Precision
Lethal Tempo
Triumph
Legend: Alacrity
Coup de Grace
Resolve
Conditioning
Overgrowth
Power Spikes
Strength by game phase
Vayne
YuumiYuumi's abilities
Passive, spells and ultimate
Periodically, when Yuumi strikes a champion with an attack or ability, she restores health to herself and the next ally she Attaches to.While Attached, Yuumi generates a special bond with her allies. The ally with the strongest bond enhances Yuumi's abilities while she is Attached to them.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 6.5s | 0s | 10s | – |
| 6 | 6.5s | 0s | 10s | 2m |
| 9 | 6.5s | 0s | 10s | 2m |
| 11 | 6.5s | 0s | 10s | 1m50 |
| 16 | 6.5s | 0s | 10s | 1m40 |
| 18 | 6.5s | 0s | 10s | 1m40 |
Playing against Yuumi
How to counter and exploit weaknesses
Focus the Yuumi host: she can't be targeted while attached, kill her host.
Punish Yuumi when she detaches to proc her passive — that's the moment she's vulnerable.
Champions with high burst can kill the host despite Yuumi's heals.
Grievous Wounds on the host reduces Yuumi's heals on her target.
Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026