Xerath vs Locke

Charge Arcanopulse (Q) to poke from long range: its range grows with the charge, but you slow down by up to 50% in the meantime.

Slow your target with Eye of Destruction (W) before Arcanopulse (Q): the center of the zone slows the most, and a slowed target dodges poorly.

Land Shocking Orb (E), then center Eye of Destruction (W) on the target: stunned, they can't dodge it, and the center slows the most.

Cast Rite of the Arcane (R) to finish a fleeing target or support a distant fight: your shots reach 5000 range, with bonus damage per champion hit.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.