Matchup
Skill matchup
Build vs Vayne
Build adapted to this matchup
Starting items
Core build
Standard
Summoner spells
87%
7%Anti AD
Anti Heal
Anti AP
Anti Tank
DPS
Precision
Lethal Tempo
Triumph
Legend: Bloodline
Cut Down
Inspiration
Triple Tonic
Cash Back
Power Spikes
Strength by game phase
Zeri
VayneVayne's abilities
Passive, spells and ultimate
Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 6s | 0s | 20s | – |
| 6 | 4s | 0s | 20s | 1m40 |
| 9 | 2s | 0s | 20s | 1m40 |
| 11 | 2s | 0s | 20s | 1m25 |
| 16 | 2s | 0s | 16s | 1m10 |
| 18 | 2s | 0s | 12s | 1m10 |
Playing against Vayne
How to counter and exploit weaknesses
Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.
Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.
Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.
Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.
Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026