Matchup

Sustained DPSHeavy AD damageDive threatSplit push

Build vs Vayne

Build adapted to this matchup

Starting items

Health Potion
x2

Core build

Locket of the Iron Solari
1HP
Zeke's Convergence
2Tank
Bandlepipes
3vs Hybride

Standard

Boots of Swiftness
4vs Slow
Celestial Opposition
5HP

Summoner spells

41485%
478%

Anti AD

Plated Steelcaps
4vs AD
Frozen Heart
5vs AD

Anti Heal

Thornmail
6vs Hybride

Anti CC

Mercury's Treads
4vs CC

Anti Tank

Void Staff
5vs Tank

Other options

Celestial Opposition
HP
Solstice Sleigh
HP
Shurelya's Battlesong
Redemption
100.0% WR1 games
InspirationInspiration
Glacial AugmentGlacial Augment
Hextech FlashtraptionHextech Flashtraption
Biscuit DeliveryBiscuit Delivery
Cosmic InsightCosmic Insight
SorcerySorcery
CelerityCelerity
Nimbus CloakNimbus Cloak
Ability HasteHealth ScalingHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
BlitzcrankBlitzcrank
VayneVayne
Favorable
Favorable
Passive

Vayne's abilities

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns

Cooldowns by spell rank

LevelQWER
36s0s20s
64s0s20s1m40
92s0s20s1m40
112s0s20s1m25
162s0s16s1m10
182s0s12s1m10

Playing against Vayne

How to counter and exploit weaknesses

1

Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.

2

Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.

3

Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.

4

Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026