Brand vs Yasuo

Hit the same target with three spells: at 3 stacks, Blaze (passive) becomes unstable and detonates 2 seconds later, dealing heavy damage around it.

Start with Conflagration (E), then Sear (Q) to stun the target while they're ablaze, and finish with Pillar of Flame (W), which deals 25% more damage to them.

Cast Conflagration (E) on a minion that's ablaze near your opponent: when the target is ablaze, the spread range doubles and reaches them.

Cast Pyroclasm (R) when several enemies are close: the torrent bounces up to 5 times, first to champions that are ablaze but not yet at 3 stacks.

Hit him with a cheap attack to trigger the Way of the Wanderer (passive) shield, then start the real trade: otherwise, it absorbs your best damage.

If you have projectiles, save them for after Wind Wall (W): it blocks them all for 4 seconds, on a 25 to 17 second cooldown. Other spells go through it.

Don't stand right behind your minions: each one gives him a target for Sweeping Blade (E), and he gets closer to you with every dash.

Get out of the line of his whirlwind, the third Steel Tempest (Q): without a knock-up, he can't cast Last Breath (R).

Judge his threat by his crit items more than his level: Way of the Wanderer (passive) raises his critical strike chance, so each crit item does more for him.