Ekko vs Naafiri

Throw Timewinder (Q) at a champion, then position so the device passes through them again on its way back: it expands into a slowing field, and the return hits again.

Hit with Timewinder (Q) out and back, and weave in the empowered auto from Phase Dive (E): the third hit triggers Z-Drive Resonance (passive), with bonus damage and speed.

Cast Parallel Convergence (W) where the fight will happen, then step into the sphere when it appears: you stun the enemies inside and gain a shield.

Engage, deal your damage, then cast Chronobreak (R): you return to where you were 4 seconds earlier, in stasis, and recover health based on what you lost.

Dodge Darkin Daggers (Q): her pack leaps onto the first champion hit, and the second dagger hits harder if you're already bleeding.

If you have AoE spells, hit her pack too: each packmate killed lowers her damage. Do it before Eviscerate (E) calls them back and heals them.

Save your targeted spells for after The Call of the Pack (W): for a brief moment, she and her pack are untargetable.

Avoid crossing the map alone against her: Hounds' Pursuit (R) lets her dash onto a champion from range, and a takedown lets her recast it.