K'Sante vs Vayne

Stack Ntofo Strikes (Q) on minions: after 2 hits, the next cast becomes a shockwave that stuns and pulls, so save it for the champion.

Charge Path Maker (W) when they throw CC at you: while charging, you're Unstoppable and take less damage, then your dash knocks back and stuns.

Cast Footwork (E) toward an ally to protect them or escape: the dash goes much farther, and you both gain a shield.

Knock your target into a wall with All Out (R): they go through it, you follow, and you hit harder at the cost of some of your health and resistances.

Don't stand with your back to a wall against her: Condemn (E) knocks you back, and if you hit terrain, you're stunned.

Take short, repeated trades: she's fragile, and on the third consecutive hit on you, Silver Bolts (W) adds true damage based on your max health.

During Final Hour (R), back off rather than risk your life: each champion she kills after damaging them extends the effect.