Matchup

Sustained DPSHeavy AD damageDive threatSplit push

Build vs Vayne

Build adapted to this matchup

Starting items

Scorchclaw Pup
Health Potion

Core build

Trinity Force
1DPS
The Collector
2vs Tank
Hexoptics C44
3DPS

Standard

Berserker's Greaves
4AS
Kraken Slayer
5DPS

Summoner spells

411100%

Anti AD

Plated Steelcaps
4vs AD
Guardian Angel
5vs AD

Anti Heal

Mortal Reminder
6vs Hybride

Anti CC

Mercury's Treads
4vs CC

Anti Tank

Lord Dominik's Regards
5vs Tank

DPS

Kraken Slayer
DPS
Infinity Edge
DPS
Rapid Firecannon
DPS
Phantom Dancer
DPS
100.0% WR2 games
PrecisionPrecision
Press the AttackPress the Attack
TriumphTriumph
Legend: AlacrityLegend: Alacrity
Coup de GraceCoup de Grace
InspirationInspiration
Magical FootwearMagical Footwear
Cosmic InsightCosmic Insight
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Early (0-15)
Mid (15-30)
Late (30+)
KindredKindred
VayneVayne
Neutral
Neutral
Neutral

Vayne's abilities

Passive, spells and ultimate

Night Hunter (P)

Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

Cooldowns

Cooldowns by spell rank

LevelQWER
36s0s20s
64s0s20s1m40
92s0s20s1m40
112s0s20s1m25
162s0s16s1m10
182s0s12s1m10

Playing against Vayne

How to counter and exploit weaknesses

1

Punish her aggressively in the early game (levels 1-5): Vayne has short range (550) and no waveclear, she's very vulnerable.

2

Buy Plated Steelcaps — they reduce her auto-attack damage which is her only source of DPS.

3

Avoid fights near walls: her E (Condemn) stuns against walls for a long duration.

4

Control Wards and Oracle Lens reveal Vayne during her invisibility (R+Q) — place them in teamfights to target her.

Source: op.gg + LTL Engine · Patch 16.9.1 · May 9, 2026