Mel vs Nautilus

Stay back and poke with Radiant Volley (Q): its projectiles explode in an area up to 950 range, and each hit applies Overwhelm.

Land an auto after each spell: Searing Brilliance (passive) adds three projectiles to it per spell cast, and enough Overwhelm executes the target.

Save Rebuttal (W) for a dangerous projectile: the barrier sends it back to its caster, and you gain a shield and move speed.

Hit your target head-on with Solar Snare (E): only the core of the orb roots, the aura around it just slows and damages.

Cast Golden Eclipse (R) to finish from range: it hits every enemy marked by Overwhelm, wherever they are, harder with each stack.

Once he hits level 2, stay behind your minions: the Dredge Line (Q) anchor hooks the first enemy hit, then the Staggering Blow (passive) auto keeps you in place.

When he casts Riptide (E) near you, stay put until it ends: its three explosions spread out around him, and running too early makes you take the next ones and their slow.

When Dredge Line (Q) misses you, keep your distance: it's his only spell to reach you, on a 14 to 10 second cooldown.

When he aims Depth Charge (R) at an ally, don't stand between them: the shockwave chases its target, and every enemy in its path takes a knock-up.