Mel vs Thresh

Stay back and poke with Radiant Volley (Q): its projectiles explode in an area up to 950 range, and each hit applies Overwhelm.

Land an auto after each spell: Searing Brilliance (passive) adds three projectiles to it per spell cast, and enough Overwhelm executes the target.

Save Rebuttal (W) for a dangerous projectile: the barrier sends it back to its caster, and you gain a shield and move speed.

Hit your target head-on with Solar Snare (E): only the core of the orb roots, the aura around it just slows and damages.

Cast Golden Eclipse (R) to finish from range: it hits every enemy marked by Overwhelm, wherever they are, harder with each stack.

Keep minions between you and Thresh: Death Sentence (Q) stuns and pulls the first unit hit, so one minion is enough to block it.

Step up when Death Sentence (Q) misses you: he keeps its full cooldown, 19 to 9 seconds, which only goes down if the hook lands.

Don't stay in his range for no reason: Flay (E) charges his autos between hits, and a charged auto hits hard early on.

Avoid being the first to break a wall of The Box (R): that one slows and deals full damage. After that, the remaining walls deal no damage.