Thresh vs Seraphine

Open with Flay (E) before Death Sentence (Q): the slow makes the hook much easier to land.

In lane, space out your autos: Flay (E) charges them passively, and the longer you wait between two autos, the more damage they deal.

Don't recast Death Sentence (Q) on reflex: the target is already being pulled toward you, and jumping on them often exposes you for nothing.

Throw Dark Passage (W) toward an ally in trouble before they need it: they can click it to come back to you, with a shield.

Place The Box (R) right after a successful hook: to escape, the target has to break a wall, and the first wall broken slows them and deals full damage.

Dodge Beat Drop (E), especially if you're already slowed: it roots a slowed target and stuns an immobilized one.

Count her basic spells and back off before the third: Stage Presence (passive) casts it twice, whether it damages, slows or shields.

Spread out from your allies against Encore (R): each champion hit extends its range, and a charmed ally near you lets it reach you.

If you can engage, target Seraphine: her kit has no dash to escape.