Twitch vs Vayne
Skill matchup
You are stronger late game. Farm safe and avoid early trades.
Build vs Vayne
Build adapted to this matchup
Recommended items for Twitch: The Collector, Fiendhunter Bolts, Infinity Edge, Berserker's Greaves, Runaan's Hurricane, Lord Dominik's Regards, Yun Tal Wildarrows, B. F. Sword.
Starting items
Core build
Standard
Summoner spells
Anti CC
Other options
Power Spikes
Strength by game phase
Vayne's abilities
Passive, spells and ultimate
Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 6s | 0s | 20s | – |
| 6 | 4s | 0s | 20s | 1m40 |
| 9 | 2s | 0s | 20s | 1m40 |
| 11 | 2s | 0s | 20s | 1m25 |
| 16 | 2s | 0s | 16s | 1m10 |
| 18 | 2s | 0s | 12s | 1m10 |
Playing as Twitch
Tips to maximize your impact
- Approach camouflaged
Approach camouflaged with Ambush (Q), then start the fight: when you leave camouflage, you gain bonus attack speed.
- Catch up with Venom Cask
Throw Venom Cask (W) at an enemy fleeing out of your range: the cloud slows them and adds a Deadly Venom (passive) stack every second.
- Poison before you contaminate
Apply as many Deadly Venom (passive) stacks as you can before Contaminate (E): each stack adds damage, and the spell hits every poisoned enemy within 1200 range.
- Shoot through their frontline
During Spray and Pray (R), stay back and aim at their carries through the frontline: your bolts pierce every enemy, with less damage after the first.
- Camouflage again after a kill
When a champion dies poisoned by Deadly Venom (passive), Ambush (Q) comes back right away: recast it to reposition in the middle of the teamfight.
Playing against Vayne
How to counter and exploit weaknesses
- Don't fight with your back to a wall
Don't stand with your back to a wall against her: Condemn (E) knocks you back, and if you hit terrain, you're stunned.
- Short, repeated trades
Take short, repeated trades: she's fragile, and on the third consecutive hit on you, Silver Bolts (W) adds true damage based on your max health.
- Don't feed her kills during her ult
During Final Hour (R), back off rather than risk your life: each champion she kills after damaging them extends the effect.
Other Twitch matchups
Patch 16.21.1