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Vayne vs Kai'Sa

Vayne
vs
Not enough games
Kai'Sa
Analyze a draft with Vayne
Sustained DPSHigh burstHeavy AP damageHeavy AD damage

You are stronger late game. Farm safe and avoid early trades.

Build vs Kai'Sa

The champion's reference build, for lack of enough games in this matchup

Recommended items for Vayne: Blade of The Ruined King, Guinsoo's Rageblade, Terminus, Berserker's Greaves, Essence Reaver, Stormrazor, Experimental Hexplate, Kraken Slayer.

Starting items

Doran's Bow
Health Potion
x2

Core build

Blade of The Ruined King
1
Guinsoo's Rageblade
2
Terminus
3

Standard

Berserker's Greaves
4AS
Essence Reaver
5

Summoner spells

ExhaustFlash55%
FlashHaste25%

Anti CC

Mercury's Treads
4vs CC

Other options

Essence Reaver
Stormrazor
Experimental Hexplate
Kraken Slayer
Infinity Edge
Fiendhunter Bolts
Trinity Force
Jak'Sho, The Protean
Mercurial Scimitar
Guardian Angel
Phantom Dancer
PrecisionPrecision
Lethal TempoLethal Tempo
TriumphTriumph
Legend: AlacrityLegend: Alacrity
Coup de GraceCoup de Grace
ResolveResolve
ConditioningConditioning
OvergrowthOvergrowth
Attack SpeedAdaptive ForceHealth Scaling

Power Spikes

Strength by game phase

Kai'Sa's abilities

Passive, spells and ultimate

Second Skin (P)

Kai'Sa's basic attacks stack Plasma, dealing increasing bonus magic damage. Allies' immobilizing effects help stack Plasma. Additionally, Kai'Sa's item purchases upgrade her basic spells to have more powerful properties.

Cooldowns

Cooldowns by spell rank

LevelQWER
310s20s16s–
68s20s16s2m10
96s18.5s16s2m10
116s17s16s1m40
166s14s13s1m10
186s14s10s1m10

Playing as Vayne

Tips to maximize your impact

  1. Three hits on the same target

    Hit the same target three times in a row, with autos or spells: on the third hit, Silver Bolts (W) adds true damage based on their max health.

  2. Tumble between autos

    Slip a Tumble (Q) between two autos: you reposition, and your next attack deals bonus damage. Its cooldown drops from 6 to 2 seconds.

  3. Pin your target to a wall

    Position yourself so that Condemn (E) pushes your target into a wall: if they hit terrain, they're stunned and take more damage.

  4. Be patient before your items

    Play safe while you're missing your first items: Vayne mostly shines later, when Silver Bolts (W) cuts through big health pools.

  5. Tumble unseen during your ult

    During Final Hour (R), each Tumble (Q) makes you invisible for a moment and comes back faster: tumble to reposition while the enemy can't target you.

Playing against Kai'Sa

How to counter and exploit weaknesses

  1. Stay near your minions

    Stay near your minions: Icathian Rain (Q) splits its missiles between nearby enemies, and on your own, you take them all.

  2. Harass her before she evolves

    If your attack range beats her 525 units, harass her early: Second Skin (passive) only evolves her spells as she buys items.

  3. Dodge her Void Seeker

    Dodge Void Seeker (W): it marks you with Plasma and reveals you, which lets Killer Instinct (R) dash onto you from very far away.

Other Vayne matchups

Patch 16.21.1