Hecarim vs Locke

Cast Devastating Charge (E) far from your target: the longer the run, the farther the knockback and the harder the hit, and Warpath (passive) turns your bonus move speed into AD.

Cast Onslaught of Shadows (R) from range: the fear from the shockwave, at the end of the dash, lasts longer after a long run.

In teamfights, recast Rampage (Q) as soon as it's back: each cast that hits adds a stack, which lowers its cooldown and raises its damage.

Activate Spirit of Dread (W) in the middle of the enemies: you gain armor and magic resist, and heal for part of the damage you and your team deal to them.

Back instead of staying in lane at low health: Silver Stake (passive) adds damage to his autos that grows with your missing health.

Trade after Ashen Pursuit (E): it's his only instant movement, and its 10-second cooldown only resets if he gets a takedown.

During Soul Ignition (W), only hit him if you can kill him: at the end, he heals back part of the last damage taken, yours included.

Marked by Purgatory (R), stay above its threshold: if you have a heal or a shield, use it, because he seals marked enemies who drop below it.

If the Purgatory (R) artifact lands, hold the area where it fell: by picking it up, Locke raises his execute threshold for each sealed champion, for the rest of the game.