Zac vs Yasuo

After Stretching Strikes (Q) on one enemy, hit a second enemy with your auto: you fling them into each other, and if they collide, they and those nearby take damage.

Pick up the chunks of Goo you shed when your spells hit: Cell Division (passive) heals you for each one, and Unstable Matter (W) comes back 1 second sooner.

Charge Elastic Slingshot (E) from the fog of war: the enemy has less time to react, and the longer the charge, the longer the knock-up on landing.

Cast Let's Bounce! (R) into the heart of their team: the first bounce knocks back each enemy hit, the following ones slow them, and you can cast Unstable Matter (W) at the same time.

Hit him with a cheap attack to trigger the Way of the Wanderer (passive) shield, then start the real trade: otherwise, it absorbs your best damage.

If you have projectiles, save them for after Wind Wall (W): it blocks them all for 4 seconds, on a 25 to 17 second cooldown. Other spells go through it.

Don't stand right behind your minions: each one gives him a target for Sweeping Blade (E), and he gets closer to you with every dash.

Get out of the line of his whirlwind, the third Steel Tempest (Q): without a knock-up, he can't cast Last Breath (R).

Judge his threat by his crit items more than his level: Way of the Wanderer (passive) raises his critical strike chance, so each crit item does more for him.