Mel vs Malzahar

Stay back and poke with Radiant Volley (Q): its projectiles explode in an area up to 950 range, and each hit applies Overwhelm.

Land an auto after each spell: Searing Brilliance (passive) adds three projectiles to it per spell cast, and enough Overwhelm executes the target.

Save Rebuttal (W) for a dangerous projectile: the barrier sends it back to its caster, and you gain a shield and move speed.

Hit your target head-on with Solar Snare (E): only the core of the orb roots, the aura around it just slows and damages.

Cast Golden Eclipse (R) to finish from range: it hits every enemy marked by Overwhelm, wherever they are, harder with each stack.

Get out of the Call of the Void (Q) zone quickly: its two portals fire after a short delay, and their projectiles silence you.

If you have CC, hit him first with a cheap attack, then wait a moment: Void Shift (passive) still ignores CC right after the first damage.

Stay away from minions hit by Malefic Visions (E): if they die, the visions jump to the nearest enemy, and his Voidlings follow them.

Take your trades before he hits level 6: after that, Nether Grasp (R) can lock you down from range while his team hits you.

When he casts Nether Grasp (R) on an ally, focus him: he channels in place, and any CC interrupts him and frees your ally.