Mel vs Zoe

Stay back and poke with Radiant Volley (Q): its projectiles explode in an area up to 950 range, and each hit applies Overwhelm.

Land an auto after each spell: Searing Brilliance (passive) adds three projectiles to it per spell cast, and enough Overwhelm executes the target.

Save Rebuttal (W) for a dangerous projectile: the barrier sends it back to its caster, and you gain a shield and move speed.

Hit your target head-on with Solar Snare (E): only the core of the orb roots, the aura around it just slows and damages.

Cast Golden Eclipse (R) to finish from range: it hits every enemy marked by Overwhelm, wherever they are, harder with each stack.

Dodge Sleepy Trouble Bubble (E): asleep, you take double damage from the hit that wakes you, often her Paddle Star! (Q).

During Portal Jump (R), aim at her starting position: she returns there after 1 second, and can't move in the meantime.

Don't walk onto a bubble left on the ground: a Sleepy Trouble Bubble (E) that hits nothing turns into a trap.

Ward the hidden spots behind walls near your lane: Sleepy Trouble Bubble (E) reaches farther over a wall, and Zoe hides there to set it up.