Vayne vs Dr. Mundo
Skill matchup
Build vs Dr. Mundo
The champion's reference build, for lack of enough games in this matchup
Recommended items for Vayne: Blade of The Ruined King, Guinsoo's Rageblade, Terminus, Berserker's Greaves, Kraken Slayer, Experimental Hexplate, Wit's End, Executioner's Calling.
Starting items
Core build
Standard
Summoner spells
Anti CC
Other options
Power Spikes
Strength by game phase
Dr. Mundo's abilities
Passive, spells and ultimate
Dr. Mundo resists the first Immobilizing effect that hits him, instead losing Health and dropping a chemical cannister nearby. Dr. Mundo can pick it up by walking over it, restoring Health and reducing this Ability's Cooldown.Dr. Mundo also has significantly increased Health regeneration.
Cooldowns
Cooldowns by spell rank
| Level | Q | W | E | R |
|---|---|---|---|---|
| 3 | 4s | 17s | 9s | – |
| 6 | 4s | 17s | 9s | 2m |
| 9 | 4s | 16.5s | 9s | 2m |
| 11 | 4s | 16s | 9s | 2m |
| 16 | 4s | 15s | 7.5s | 2m |
| 18 | 4s | 15s | 6s | 2m |
Playing as Vayne
Tips to maximize your impact
- Three hits on the same target
Hit the same target three times in a row, with autos or spells: on the third hit, Silver Bolts (W) adds true damage based on their max health.
- Tumble between autos
Slip a Tumble (Q) between two autos: you reposition, and your next attack deals bonus damage. Its cooldown drops from 6 to 2 seconds.
- Pin your target to a wall
Position yourself so that Condemn (E) pushes your target into a wall: if they hit terrain, they're stunned and take more damage.
- Be patient before your items
Play safe while you're missing your first items: Vayne mostly shines later, when Silver Bolts (W) cuts through big health pools.
- Tumble unseen during your ult
During Final Hour (R), each Tumble (Q) makes you invisible for a moment and comes back faster: tumble to reposition while the enemy can't target you.
Playing against Dr. Mundo
How to counter and exploit weaknesses
- Stay behind your minions
Stay behind your minions: Infected Bonesaw (Q) hits the first enemy, and it's his only ranged spell to slow you.
- Save your best CC for later
If you have several CCs, lead with the least valuable: Goes Where He Pleases (passive) lets him resist the first immobilizing effect.
- Don't focus him during his R
Don't keep hitting him during Maximum Dosage (R): he regenerates part of his max health for the whole duration and gains move speed.
- Target his carries in teamfights
In teamfights, target his carries rather than him: Goes Where He Pleases (passive) gives him far stronger health regen than normal.
Other Vayne matchups
Patch 16.21.1